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06/24/2020

Scientific news

A basic physical mechanism enables cell migration in absence of adhesion

Many cell types within the organism bind to their environment via specific adhesion molecules (integrins). In a recent study published in Nature, led by a group at IST Austria, the group of R. Voituriez (LJP, IBPS) proposed a new physical mechanism of cell migration that works in absence of any adhesion to the environment. [...]

05/20/2020

Scientific news

PhyloSofS

The LCQB proposes PhyloSofS, the first automated tool to reconstruct plausible evolutionary scenarios explaining a set of observed transcripts, and to generate 3D molecular models of the protein isoforms. [...]

04/10/2020

Scientific news

Alexandre Mourot awarded by the Human Frontier Science Program

Alexandre Mourot has been awarded a prestigious program grant by the HFSP together with his collaborator Graham Ellis-Davies. The goal of this project is to manipulate neurotransmitter receptors of the mouse brain using cell-type specific and photocontrollable drugs, activated with near-infrared light, within the behaving mouse. [...]

03/25/2020

Prizes and distinctions

A CNRS bronze medal awarded to Claude Loverdo

Claude Loverdo, researcher in biophysics at the Jean Perrin laboratory, modeler of bacterial and viral population dynamics, received a CNRS Bronze Medal. [...]

03/18/2020

Scientific news

A cloak of invisibility for glutamate

In this article published in the journal PNAS, Alexandre Mourot and Philippe Faure's team, have developed a new "caged" glutamate with biological and photochemical properties that enable, for the first time, experiments in behaving mice. [...]

02/22/2020

Scientific news

GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects

GEMME was develop by Alessandra Carbone's team. It is a fast, scalable and simple method to predict mutational landscapes from natural sequences. It demonstrates how deleterious effects of a protein mutation are identified by looking at the closest known sequence accepting the mutation in the evolutionary tree of sequences and at its epistatic changes. [...]

01/30/2020

Scientific news

RNA Modification: a new way to regulate gene expression

As part of an international collaboration on RNA modifications the team of Clément Carré and Laure Teysset - in collaboration with the ARTbio platform - have just brought to light two Drosophila genes whose products are capable of modifying tRNAs. [...]

01/20/2020

Scientific news

Cryptochrome, a protein involved in brain repair

A team of researchers from the Institut de Biologie Paris-Seine (IBPS - Sorbonne University/CNRS) led by Rachel Sherrard, professor at Sorbonne Université has studied the capacity of low-intensity magnetic stimulation to induce brain repair. Published in Science Advances, their work demonstrates, for the first time, a mechanism underlying this repair: function of the protein cryptochrome. [...]

01/07/2020

Scientific news

A transient wave of perinatal hematopoiesis in vertebrates

Researchers from the Institut de Biologie Paris-Seine are demonstrating the existence of a new hematopoietic wave from resident hemogenic endothelial cells in the bone marrow of the late fetus and young adult. [...]

09/30/2019

Prizes and distinctions

An ERC grant for Anne-Florence Bitbol from the LJP

In September 2019, Anne-Florence Bitbol from the LJP obtained a "Starting Grant" from the ERC. This grant, intended for young researchers, is allocated for 5 years. It will enable her to set up the project entitled "Optimization and historical contingency in living systems: a biophysical approach" (OptimHist). [...]

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