Valérie Goguel

  • Area Manager's office
  • Team / Theme Scientific Affairs
  • Status Staff scientists
  • Address Cassan, bâtiment B, étage 7, porte 701B, case courrier 25, 7 quai Saint Bernard, 75 252 PARIS CEDEX
  • Telephone number +33 (0) 1 44 27 81 43
  • Email

Resume

Position

CNRS Chargée de Recherche Hors Classe (CRHC)

Education

2001 HDR (Habilitation à Diriger des Recherches)
1990 PhD Molecular Biology

Research Experience 

2006-2019 ESPCI, Brain Plasticity (Paris, France) – Dr. Thomas Préat
“Memory formation in Drosophila”

1999-2006 CEA/Saclay (Saclay, France) – Dr. André Sentenac, Dr. Michel Werner
"Control of mRNA and rRNA synthesis in yeast”

1992-1999 Ecole Normale Supérieure (Paris, France) – Pr. Claude Jacq
“A new Cycline-Dependent Kinase involved in transcription in yeast”

1990-1992 Post-doc Brandeis University (MA, USA) – Pr Michael Rosbash
“Splice site selection in yeast”

1985-1989 PhD Ecole Normale Supérieure (Paris, France) – Pr Claude Jacq
“Yeast RNA maturase and DNA endonuclease: biogenesis and relationship”

Supervision    

  • 6 PhD students
  • 8 M2 internships
  • ESPCI 3rd year internships
  • Professional observation courses (College students)
  • Framed personal work (TPE High school students)
  • 2 Engineers and 2 Technicians (2008-2018)
  • Supervision of the Drosophila Facility staff

Selected publications

Turrel, O., Rabah Y., Plaçais, PY., Goguel, V.* and Preat, T.* (2020) Drosophila Middle-Term Memory: Amnesiac is Required for PKA activation in the Mushroom Bodies, a Function Modulated by Neprilysin 1. J Neurosci 40:4219-4229.

Turrel, O., Lampin-Saint-Amaux, A., Preat, T. and Goguel, V. (2016) Drosophila Neprilysins Are Involved in Middle-Term and Long-Term Memory. J Neurosci. 36:9535-9546.

Bourdet, I., Preat, T. and Goguel, V. (2015). The Full-Length Form of the Drosophila Amyloid Precursor Protein Is Involved in Memory Formation. J Neurosci 35: 1043- 1051.

Bouchoux, C., Hautbergue, G., Grenetier, S., Carles, C., Riva, M. and Goguel, V. (2004) CTD kinase I is involved in RNA polymerase I transcription. Nucleic Acids Res 32(19): 5851-5860.

Hautbergue, G. and Goguel, V. (2001) Activation of the Cyclin-Dependent Kinase CTDK-I requires the heterodimerization of two unstable subunits. J. Biol. Chem. 15: 8005-8013.

Goguel, V. and Rosbash, M. (1993) Splice site choice and splicing efficiency are positively influenced by pre-mRNA intramolecular base pairing in yeast. Cell 72: 893-901.