Nos conférences en replay

Séminaire du 9 juin 2017

Universal genetic code as a key for understanding RNA-protein interactions - (Re)voir la vidéo

Bojan Zagrovic, MPFL & Université de Vienne, Autriche.

Résumé : The relationship between mRNA and protein sequences as embodied in the universal genetic code is a cornerstone of modern-day molecular biology. In this presentation, I will provide evidence supporting a novel claim that the genetic code can actually be seen as a Rosetta stone for understanding mRNA-protein interactions in general. Conversely, I will defend a claim that RNA-protein interactions could have been an important driving force behind the origin of the genetic code. [...]

Séminaire du 3 mars 2017

Understanding cellular heterogeneity - (Re)voir la vidéo

Sarah Teichmann, EMBL-EBI, Cambridge, Royaume-Uni.

Résumé : From techniques such as microscopy and FACS analysis, we know that many cell populations harbour heterogeneity in morphology and protein expression. With the advent of high throughput single cell RNA-sequencing, we can now quantify transcriptomic cell-to-cell variation. I will discuss technical advances and biological insights into understanding cellular heterogeneity in T cells and ES cells using single cell RNA-sequencing. [...]

Séminaire (Décalé) du 17 février 2017

Biomimétisme : enjeux et opportunités - (Re)voir la vidéo

Kalina Raskin, CEEBIOS, Centre Européen d'Excellence en Biomimétisme de Senlis.

Résumé : Le biomimétisme (bio = vie, mimesis = imiter) est une stratégie d’innovation qui consiste à s’inspirer des organismes vivants pour faire évoluer les technologies et sociétés humaines vers plus de sobriété, d'efficacité et de respect de l’environnement. Des exemples illustreront l’application de cette approche aux domaines aussi divers que l’énergie, la chimie douce, les éco-matériaux... [...]

Séminaire du 3 février 2017

Cancer cell of origin and tumor heterogeneity - (Re)voir la vidéo

Cédric Blanpain, IRIBHM, Université Libre de Bruxelles, Belgique.

Résumé : For the vast majority of cancers, the cell at the origin of tumor initiation is still unknown. We are using novel genetic approach to identify the cell lineage at the origin of the most frequent epithelial cancers in humans. [...]

Séminaire du 6 janvier 2017

LUCA, the universal tree of life, and the origin of eukaryotes - (Re)voir la vidéo

Patrick Forterre, Institut Pasteur, Paris.

Résumé : The nature of LUCA, the topology of the universal tree of life, and the origin of eukaryotes are controversial issues. Recently, several authors have published molecular phylogenetic analyses suggesting that eukaryotes correspond to an archaeal branch (so we are ourselves archaea) and that early branching archaea and bacteria were nano-sized organisms. [...]

Séminaire du 4 novembre 2016

Axon regeneration in C. elegans: genes, themes and dynamics - (Re)voir la vidéo

Andrew ChisholmUniversity of California at San Diego (UCSD), United States.

Résumé : The ability of axons to regenerate after injury is a fundamental property of animal neurons. Work in a variety of systems has suggested that the molecular mechanisms of axon regeneration may be highly conserved. Genetic studies in C. elegans have highlighted the roles of Calcium dynamics, DLK MAPK signaling cascades, and posts-transcriptional controls at the level of RNA splicing. [...]

Séminaire du 3 juin 2016

Adapting to a stressful start in life - (Re)voir la vidéo

Alex Gould, Francis Crick Institute, Londres, UK.

Résumé : Animals often encounter stressful environments during development and so have evolved numerous different coping mechanisms. In mammals, it is known that one important strategy for surviving nutrient deprivation is to protect or spare the growth of critical organs such as the CNS at the expense of others. [...]

Séminaire du 20 mai 2016

Evaluating genetic adaptation and epigenetic response to pathogen pressures - (Re)voir la vidéo

Lluis Quintana-MurciInstitut Pasteur, Paris.

Résumé : Infectious diseases have been a major cause of human mortality, so natural selection is expected to act strongly on host defence genes. This is particularly expected for innate immunity genes, as they represent the first line of host defence against pathogens. I will present different cases of how some of these genes and the pathways they trigger have been targeted by natural selection, helping to delineate genes that fulfil essential functions in host defence, with respect to those exhibiting higher immunological redundancy. [...] 

Séminaire (Décalé) du 18 mars 2016

Mais que fait la police... scientifique ? - (Re)voir la vidéo

Frédéric Dupuchdirecteur de l'Institut National de Police Scientifique.

Résumé : Frédéric Dupuch retrace l'histoire de la police scientifique et décrit son organisation et ses domaines de compétence, en s’appuyant sur des exemples d’affaires plus ou moins récentes. Il passe en revue les diverses techniques utilisées par la police scientifique, et montre l’importance grandissante de la science dans les enquêtes policières. [...]